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Dr. Martín Medrano

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Profesor de Medio Tiempo

Correo eletrónico: ma.medrano@ce.pucmm.edu.do

Oficina: Edificio de la Facultad de Ciencias de la Salud, PUCMM, Campus Santiago.

Teléfono: 809-580-1962 ext. 4231

Researchgate


Publicaciones

Libros

  • Capítulo 1, Criterios Diagnósticos. Incidencia. Hipertensión Arterial como Factor de Riesgo. En: Hipertensión arterial en Geriatría. F Guillen Llera editor. Publicaciones Sandoz, 1986, Barcelona, pp : 12-30.
  • Introducción a la Medicina Geriatrica. Ediciones UTESA, 1992. Santiago.
  • Capítulo V. Demencia vascular y Alzheimer. En: Patología Neurosiquiátrica y Geriátrica. F Angeles editor. Editorial Taller, 1992.
  • Capítulo 25: La Infección en Geriatria. En Avances en Geriatría. J M Ribera Casado Editor. Editorial Gafos, España 2004. Madrid, p : 457-469
  • Suplemento Especial del Periódico Hoy. Semana del Cerebro. Editor 4 abril 2006.
  • Capítulo Insuficiencia Cardíaca Crónica. En Geriatría, editor Dr. Bermejo, Panama. 2016

Publicaciones en Revistas Indexadas (Peer Review)

  • Martin Medrano, Rebeca Lopez Rosario, Anyolina Nuñez Payano, Natacha Reynoso Capellan. Burden, anxiety and depression in caregivers of Alzheimer patients in the Dominican Republic. Dement Neuropsychol 2014 december;8(4):384-388.
  • Lee Joseph, Kahn Amanda, Cheng, Rong, Reitz Chritiane, Vardarajan Badri, Lantigua Rafel, Medrano, Martin, Jimenez-Velazques Ivonne, Williamson, Jennifer, Nagy Peter, Mayeux Richard. Disease-related mutations among Caribbean Hispanics with familial dementia. Molecular Genetics and Genomic Medicine 2014 sept, 2(5): 430-437.
  • Martin Medrano, Juanly Rodriguez, Massiel Paulino, Bienvenido Veras. Prevalence of vascular risk factors in hispanics with familial Alzheimer´s disease. The Journal of Nutrition, Health & Aging 2013, vol 17, supplement 1,S 802-803.
  • Martin Medrano, Sergio Diaz, Carolina Medrano, Manuel Ramos, Lissette Otero, Juanly Rodriguez. Sarcopenia prevalence in octogenarians and nonagenarians in a developing country: Advances Santiago Aging Study (SAS). The Journal of Nutrition, Health & Aging, 2013, vol 17, suplement 1,S 574.
  • Reitz C, Tokuhiro S, Clark LN, Conrad C, Vonsattel JP, Hazrati LN, Palotás A, Lantigua R, Medrano M, Z Jiménez-Velázquez I, Vardarajan B, Simkin I, Haines JL, Pericak-Vance MA, Farrer LA, Lee JH, Rogaeva E, George-Hyslop PS, Mayeux R. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk.Ann Neurol. 2011 Jan;69(1):47-64. doi: 10.1002/ana.22308.
  • Familial aggregation of dementia with Lewy bodies.
  • Nervi A, Reitz C, Tang MX, Santana V, Piriz A, Reyes D, Lantigua R, Medrano M, Jiménez-Velázquez IZ, Lee JH, Mayeux R. Familial aggregation of dementia with Lewy bodies. Arch Neurol. 2011 Jan;68(1):90-3. doi: 10.1001/archneurol.2010.319.
  • Lee JH, Cheng R, Barral S, Reitz C, Medrano M, Lantigua R, Jiménez-Velazquez IZ, Rogaeva E, St George-Hyslop PH, Mayeux R. Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals.
  • Arch Neurol. 2011 Mar;68(3):320-8. doi: 10.1001/archneurol.2010.292. Epub 2010 Nov8
  • Nervi A, Reitz C, Tang MX, Santana V, Piriz A, Reyes-Dumeyer D, Lantigua R, Medrano M, Jiménez-Velázquez IZ, Lee JH, Mayeux R. Comparison of clinical manifestations in Alzheimer disease and dementia with Lewy bodies.
  • Arch Neurol. 2008 Dec;65(12):1634-9. doi: 10.1001/archneur.65.12.1634.
  • Lee JH, Cheng R, Santana V, Williamson J, Lantigua R, Medrano M, Arriaga A, Stern Y, Tycko B, Rogaeva E, Wakutani Y, Kawarai T, St George-Hyslop P, Mayeux R. Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease.Arch Neurol. 2006 Nov;63(11):1591-8.
  • Romas SN, Mayeux R, Tang MX, Lantigua R, Medrano M, Tycko B, Knowles J. No association between a presenilin 1 polymorphism and Alzheimer disease.
  • Arch Neurol. 2000 May;57(5):699-702.
  • Lee JH, Cheng r, Barral s, Reitz C, Medrano M, lantigua R, Jimenez-Velasquez IZ, Rogaeva E, St Geaorge-Hyslop PH, Mayeux R. Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Cariobbean Hispanic individuals. Arch Neurol.2011 Mar; 68(3):320-8
  • Joseph H Lee- Rong Cheng- Ekaterina Rogaeva- Yan Meng- Yaakov Stern- Vincent Santana- Rafael Lantigua- Martin Medrano- Ivonne Z. Jimenez Velazquez- Lindsay A. Farrer- Peter St. George-Hyslop- Richard Mayeux. Further examination of the candidate gene in chromosome 12p13 locus for late-onset Alzheimer disease. Neurogenetics 2008, 9:127-138.
  • Angela Nervi MD, Christiane Reitz MD PhD, Ming-Xin Tang PhD, Vincent Santana MBA, Angel Piriz MD, Dolly Reyes BS, Rafael Lantigua MD, Martin Medrano MD, Ivonne Jimenez MD, Joseph Lee DrPH, Richard Mayeux MD MSc. Comparison of clinical manifestation in familial Alzheimer´s disease and dementia with Lewy Bodies. Arch Neurolo 2008, dec 65(12): 1634-9.
  • Rafael Lantigua, Vincent Santana, Martin Medrano, Hoseph H. Lee, Yaakov Stern, Benjamin Tycko, Richard Mayeux, Genetic Of Alzheimer Disease in Caribbean Hispanic. Procceding 10 International Congress alzheimer Disease. Journal Alzheimer´s Disease, Sept 2006
  • Joseph H. Lee, Hye-Seung Lee, Rong Cgeng, Vincent Santana, Jennifer, Williams, Rafael Lantigua, Martín Medrano, Benjamin Tycko, Ekaterina Rogaeva, Peter St. George Hyslop, Yaskov Stern, Richard Mayeux, Fine Mapping of 12P for Memory Traits a Complementary Approach to understanding the Genetics of Alzheimer Disease. Procceding 10 International Congress Alzheimer Disease. Journal alzheimer´s Disease, Sept 2006.
  • Lee J, Cheng R, Santana V, Williamson J, Lantigua R, Medrano M, Arriaga L, Stern Y, Tycko B, Rogaeva E, Wakutani Y, Kawari T, St George-Hyslop, Mayeux R. Expanded Genome-Wide scan implicates a Novel Locus at 3q28 among Caribbean hispanics with familial Alzheimer´s Disease. Arch Neurol 2006; 63:1591-1598
  • Martin Medrano, Rafael Lantigua, Vincent Santana, Joseph H. Lee, Yaakov Stern, Benjamin Tycko, Richard Mayeux. Vascular Risk Factors in Hispanics with Familial Alzheimer’s Disease. Procceding 10 International congress Alzheimer Disease. Journal Alzheimer´s Disease. Sept 2006
  • G.A. Rippon, MD; M.-X. Tang, PhD, J.H. Lee Dr PH; R. Lantigua, MD; M. Medrano, MD; And R. Mayeux, MD, MSc. Familial alzheimer disease in Latinos. Interaction between APOE stroke, and estrogen replacement. Neurology 2006; 66: 35-40.
  • Athan E, Williamson J, Ciappa A, Santana V, Roms SN, Lee JH, Zadroga HR, Lantigua R, Medrano M, Torres M-B, Arawaka S, Rogaeva Song Y, Sata C, Kawarai T, St George Hyslop , Stern Y, Tycko B, Mayeux R. A novel founder mutation Presenilin 1 causing familial, early onset Alzheimer’s disease in Caribbean Hispanics. JAMA 2001; 286 (18):2257-2263.
  • Mayeux R, Lee JH, Romas SN, Mayo D, Santana V, Williamson J, Ciappa A, Rondon HZ, Estevez P, Lantigua R, Medrano M, Torres M, Stern Y, Tycko B, Knowles JA, Chromosome-12 mapping of late-onset Alzheimer’s disease among Caribbean Hispanics. Am J Hum Genet. 2002; 70 (1):237-243.
  • Romas SN, Santana V, Williamson J, Ciappa A, Lee JH, Rondon HZ, Estevez P, Lantigua R, Medrano M, Torres M, Stern Y, Tycko B, Mayeux R. Familial Alzheimer disease among Carbbean Hispanics: a reexamination of its associatrion with APOE . Arch Neurol 2002.; 59(1) 87-91.
  • R. Mayeux, J H Lee, S N Romas, D. Mayo, V. Santana, J. Williamson, C. Ciappa, H Z Rondon, P Estevez, R. Lantigua, M. Medrano, M. Torres, Y Stern, B Tycko and A. Knowles. Chromosome- 12 Mapping of Late- onset alzheimer Disease among Caribbean Hispanics. Am J. Hum Genet 2002: 70: 237-243.
  • J H Lee, R Mayeux, D Mayo, J Mo, V Santana, J Williamson, A Flaquer, A Ciappa, H Rondon, P Estevez, R Lantigua, T Kawarai, A Toulina, M Medrano, M Torres, Y Stern, B Tycko, E Rogaeva, P St George-Hyslop, J Knowless. Fine Mapping of 10q and 18q for Alzheimer Disease in Caribbean Hispanics. Mol Psychiatry 2004; 9(11): 1042-51
  • Lee JH, Cheng R, rogaeva E, Meng Y, Stern Y, Santana V, Lantigua R, Medrano M, Jimenez-Velasquez I, Farrer LA, St George-Hysloop P, Mayeux R. The Chromosome 12p13 locus for late-onset Alzheimer´s disease (In Press Neurology)
  • J H. Lee, R Mayeux, D Mayo, V Santana, J Williamson, A Flaquer, A Ciappa, Hz Rondon, P Estevez, R Lantigua, M Medrano, M Torres, Y Stern, Btycko, JA Knowles. A Genome Scan for late-onset Alzheimer Disease Among Caribbean Hispanics.
  • Stavra Nicole Romas, MD; Richard Mayeux, MD, MSc; Ming-Xin Tang, PhD; Rafael Lantigua, MD; Martín Medrano, MD; Benjamin Tycko,MD,PhD; James nowles,MD, PhD. No Association Between a Presenilin 1 Polymorphism and Alzheimer Disease. Arch Neurol 2000; 57:699-702.
  • Lee JH, Barral S, Cheng R, Charcon I, Santana V, Williamson J, Lantigua R, Medrano M, Jimenez-Velasquez I, Stern Y, Tycko B, Rogaeva E, Wakutani Y, Kawarai T, St George-Hyslop P, Mayeux R. Age-at onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer´s disease . Neurogenetics 2008 feb; 9(1): 51-60.
  • Romas SN, Mayeux R, Rabinowitz D, Tangs m-T, Rondon H, Lantigua R, Medrano M, Tycko B et al. The deletion polymorphism and VAL1000Iie in alfa 2 macroglobulin and Alzheimer Disease in Caribbean Hispanics.Neuroscience Letters 2000: 279: 133-136.
  • Medrano M, Vargas G , Bernardi B y Rey López. Sordera Súbita y Fiebre de Origen Desconocido como forma de presentación de la Arteritis Temporal. Revista AMS 1987; 6(2): 83-84.
  • Medrano M, Cuervas- Mons V, Canton T, Albillos A, Montes J y Barbadillo R. Absceso Hepatico secundario a quiste Hidatidico. Analisis de 35 casos. Rev Clin Esp 1986, 290: 532-536.
  • M. Medrano, Uzcanga E, et a. Arteritis de la Temporal, una enfermedad Geriatrica. Rev Esp Ger y Gerontol. 1985; 41: 138
  • Cuervas V, Medrano M, Barbadillo r. Hepatoma. Análisis de 100 casos. Gastroenterología y Hepatología 1984; 18 (5): 185-187.
  • J. Montes, V Cuervas-Mons, M zarraga, T Canton, A Albillos, M Medrano, R Barbadillo. Sindromes Paraneoplasicos del hepatoma. Gastroenterologia y Hepatologia, 1984; 7: 479-483.
  • Medrano M. Farmacos Hepatotoxicos en Geriatria. Algoritmo de Seguimiento. Rev Esp Ger Gerontol 1984; 19 (3): 153-156.
  • Medrano M: carta al director: Debe cambiarse la edad en el concepto de paciente geriatrico ? Rev Esp Ger Geront. 1984; 20 (4): 16